In March 2007, ALF announced the winners of its 2007 Research Awards. Sixteen scientists representing 12 medical and research institutions were awarded more than $1.2 million to support their research in the areas of autoimmune hepatitis, biliary atresia, cirrhosis, cholestatic liver disease, chronic liver inflammation, hepatitis B, hepatitis C, liver fibrosis, liver regeneration, non-alcoholic fatty liver disease and primary biliary cirrhosis.
ALF is proud to support these research efforts and hopeful that they will bring us closer to finding cures for liver disease.
2007 Research Awardees
Liver Scholar Awards - $225,000
- Jorge Allina, MD, Mount Sinai School of Medicine
Project Title: Progression of Non Alcoholic Fatty Liver Disease and Air Pollution
Topic: NAFLD - Ayman A Koteish, MD, Johns Hopkins University
Project Title: Epithelial-to-Mesenchymal Transition: its Role in Hepatic Fibrogenesis
Topic: Cogential Hepatic Fibrosis, Cirrhosis - Ping Lam, PhD, Yale University
Project Title: Molecular Determinants Controlling Liver Bile Salt Export Pimp (BSEP/ABCB11) Trafficking and Function
Topic: Cholestatic Liver Disease
Hep C Liver Scholar Special Research Initiative - $225,000
- Glenn C. Randall, PhD, The University of Chicago
Project Title: USP18 as a target to improve interferon therapy of HCV
Topic: Hepatitis C
PBC Seed Grant Special Research Initiative - $200,000
- Shi-Ying Cai, PhD, Yale University School of Medicine
Project Title: Ursodeoxycholic Acid and Retinoic Acid Combinational Treatment for Primary Biliary Cirrhosis
Topic: PBC
Postdoctoral Research Fellowships - $12,500
- Samuele De Minicis, MD, Columbia University
Project Title:Role of Phagocytic and Non-phagocytic NADPH Oxidase in Hepatic Fibrogenesis
Topic: Liver Fibrosis and NADPH - Christian Klotz, PhD, New York University, School of Medicine
Project Title: Modulation of Kupffer Cell Function by Malaria Sporozoites
Topic: Malaria - Hui Li, PhD, University of Washington, School of Medicine
Project Title: Mononuclear Cells in HCV Infected and HCV/HIV Coinfected Patients
Topic: Hepatitis C - Pallavi B Limaye, PhD, University of Pittsburgh School of Medicine
Project Title: Role of HGF and EGF Mediated Signaling in Transdifferentiation of Hepatocytes into Biliary Epithelium
Topic: Cholestatic Liver Disease - Marta Martinez-Vincente, PhD, Albert Einstein College of Medicine, Marion Bessin Liver Center
Project Title: Role of Iysosomal m TOR in Regulation of Liver Autophagy
Topic: Liver Carcinoma and Aging - Alexander G. Miethke, MD, Cincinnati Children's Hospital Medical Center
Project Title: The Role of Regulatory T Cells in the Pathogenesis of Experimental Biliary Atresia
Topic: Biliary Atresia - Philippa H. Newell, MD, Mount Sinai School of Medicine
Project Title: Targeting the Canonical WNT Pathway In Hepatocellular Carcinoma: The Effect Of Small Molecule ICG-001 In HCC Cell Lines And In Nude Mouse Xenografts
Topic: Hepatitis C - Christoph H. Oesterreicher, MD, Columbia University
Project Title: Role of ACE2 and its Substrates in Liver Injury and Fibrogenesis
Topic: Liver Fibrosis - Alexander Weymann, MD, Washington University
Project Title: Functional Analyses of PPAR Gamma Signaling During Liver Regeneration
Topic: Liver Regeneration - Lauren A. .Zenewicz, PhD, Yale University
Project Title: IL-22-mediated Protection to T Cell-mediated Inflammation in the Liver
Topic: Chronic Liver Inflammation, Fibrosis, and Hepatitis B - Jing Wang, PhD, Dartmouth Medical School
Project Title: Isolation and Analysis of Liver Antigen-specific T Helper Cell Clones in a Mouse Model of Autoimmune Hepatitis
Topic: Autoimmune Hepatitis
For more information about research awards call 1-800-Go-Liver today.
Page updated: March 14th, 2007