For Patients Caregiver Tips and Advice For Medical Professionals

Hepatic Encephalopathy

Hepatic Encephalopathy, sometimes referred to as portosystemic encephalopathy or PSE, is a condition that causes temporary worsening of brain function in people with advanced liver disease. When your liver is damaged it can no longer remove toxic substances from your blood. These toxins build up and can travel through your body until they reach your brain, causing mental and physical symptoms of HE.

  • Will I get routine labs to monitor my ammonia levels?
  • What is the status of my liver?
  • Do I have liver damage?
  • Will I need a liver transplant?
  • (If I need a liver transplant) – Which transplant centers are located in my state?
  • What is my approximate MELD score?
  • What dosage of lactulose will I be taking? How often should I take it?
  • If lactulose alone does not manage my HE, will Xifaxan be added?
  • What can I anticipate with HE? Will I have mood changes?
  • If I begin to have issues with remembering my medications – will it be possible to have a visiting nurse come to my home?
  • What kinds of information can I share with my friends and family about my condition?
  • Will I be able to continue to work to my full capacity?
  • Will I be able to drive?

Support Groups Near You

Visit the American Liver Foundation support group page here to find the closest support group to you.

Online Support Groups

Visit the American Liver Foundation online support group at Inspire…

PBC Support Group on Facebook
Visit the American Liver Foundation Primary Biliary Cholangitis support group on Facebook. For more details, click here…

Visit to learn more about Hepatic Encephalopathy.

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