Liver Disease Information
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American Liver Foundation
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Explore this section to learn more about liver cancer, including a description of the disease and how it's diagnosed.
Why is the liver important?
The liver is the second most important organ in your body and is located under your rib cage on the right side. It weighs about three pounds and is shaped like a football that is flat on one side.
The liver performs many jobs in your body. It processes what you eat and drink into energy and nutrients that it stores for your body to use. The liver also removes harmful substances from your blood.
What is liver cancer?
Liver cancer is the growth and spread of unhealthy cells in the liver. Cancer that starts in the liver is called primary liver cancer. Cancer that spreads to the liver from another organ is called metastatic liver cancer.
About 30,000 Americans are diagnosed with primary liver cancer each year. Primary liver cancer is one of the cancers on the rise in the United States. Primary liver cancer is about twice as common in men than in women.
What causes liver cancer?
There are several risk factors for liver cancer:
What are the symptoms of liver cancer?
Symptoms may include fatigue, bloating, pain on the right side of the upper abdomen or back and shoulder, nausea, loss of appetite, feelings of fullness, weight loss, weakness, fever, and jaundice (yellowing of the eyes and the skin).
How is liver cancer diagnosed?
A physical examination or imaging tests may suggest liver cancer. To confirm a diagnosis, doctors may use blood tests, ultrasound tests, computed tomography (CT) scans, magnetic resonance imaging (MRI), and angiograms. Your doctor may also need to do a liver biopsy. During a biopsy, a small piece of liver tissue is removed and studied in the lab.
How is liver cancer treated?
Liver cancer treatment depends on:
Treatment options if the cancer has not spread and the rest of the liver is healthy are:
Other treatment options if surgery and transplant are not possible include:
For cancer that has not spread outside the liver:
For cancer that has spread outside the liver:
What is the outlook for patients with liver cancer?
A successful liver transplant will effectively cure liver cancer, but it is an option for only a small percentage of patients. Surgical resections are successful in only about one out of three cases. However, scientists are experimenting with several promising new drugs and therapies that could help prolong the lives of people with liver cancer.
What is the best way to reduce the risk of liver cancer?
Steps to reduce the risk of liver cancer include: